To study the prevalence of cutaneous leishmaniasis and its effects on the hematological profile of patients in district waziristan wana

Aziz Rehman; Omer Khiam; Inkishaf Alam; Saddam Hussain; Qaisar Ali; Muhammad ESSA Khan; Asad Nisar; Waqas Ahmad

doi:10.22376/

Authors

Ihtisham UL Haq Department of Rehabilitation & Allied Health Sciences, Riphah International University, Pakistan
Omer Khiam Institute of Biotechnology and Genetics Engineering, University of Agriculture, Peshawar, Pakistan
Inkishaf Alam Gulrang Institute of Nursing Thana Malakand, Pakistan
Saddam Hussain Department of Allied Health Sciences, North West Institute, Peshawar, Pakistan
Qaisar Ali Department of Health and Biological Sciences, Abasyn University, Peshawar, Pakistan
Muhammad ESSA Khan Department: Amal College of Health Management Sciences and Institute of Nursing, Thana Malakand agency
Asad Nisar Department of Allied Health Sciences, Iqra National University, Peshawar, Pakistan
Waqas Ahmad Department of Health Sciences, Batkhela College of Nursing, Pakistan

Abstract

Background: Cutaneous leishmaniasis is an important health problem in Waziristan, especially in Wana and it impairs the local population both clinically and hematologically. Notwithstanding its spread, there is a dearth of studies on the effect of the disease on the hematological profile of its victims. Aim and Objectives: This study aimed to determine the prevalence of cutaneous leishmaniasis and assess its effects on the hematological profile of patients in Waziristan, Wana. The objectives were to identify the prevalence of the disease, analyze the hematological abnormalities associated with it, and examine its distribution across different age groups (0-50 years). Materials and Methods: A total of 200 samples were collected from various hospitals in Waziristan Wana, representing a population of 152,891 people. including skin lesions, were examined using microscopy, to identify Leishmania species. Blood samples were analyzed for hematological abnormalities, including normocytic normochromic anemia, neutropenia, monocytosis, lymphocytosis, and thrombocytopenia, using automated hematology analyzers. Results: The study revealed a high prevalence of cutaneous leishmaniasis, with significant hematological abnormalities observed, particularly normocytic normochromic anemia and thrombocytopenia. The face was identified as the most commonly affected site, with the younger age group (0-16 years) showing more pronounced hematological changes. Conclusion: This paper highlights the high incidence of cutaneous leishmaniasis in Waziristan and its significant effect on the hematological character of patients. The results point to the necessity of specific medical measures and preventive actions in the area.

Keywords:

Cutaneous leishmaniasis, hematological profile, prevalence, public health

DOI

https://doi.org/10.22376/

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