Brief review on ongoing clinical trials on covid-19 vaccines

Authors

  • Roshini Dommeti III/VI Pharma-D, Koringa College of Pharmacy, Korangi-533461, Tallarevu Mandal, Kakinada District, Andhra Pradesh, India
  • Naga Subrahmanyam S Professor And HOD, Department of Pharmacy Practice, Koringa College of Pharmacy, Korangi-533461, Tallarevu Mandal, Kakinada District, Andhra Pradesh, India.
  • M. Venkata Padma Assistent Professor, Koringa College of Pharmacy, Korangi-533461, Tallarevu Mandal, Kakinada District, Andhra Pradesh, India.
  • Manoj Sai Prasad Dommeti III/VI B. tech, AU College of engineering, Andhra University-Visakhapatnam.

Abstract

Five years into mass deployment, COVID-19 vaccine R&D remains active, with trials now concentrating on variant-adapted boosters, mucosal (intranasal/oral) candidates aimed at blocking transmission, and broadly protective (pan-coronavirus) vaccines. Recent Phase 1–3 studies are refining antigen choice (e.g., KP.2/JN.1-era variants), delivery routes, and durability, while expanding evaluation in older adults and other high-risk groups. This review summarizes the current clinical pipeline and trial directions using the WHO vaccine landscape, ClinicalTrials.gov records, and recent peer-reviewed reports.

DOI

https://doi.org/10.70604/

References

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2. ClinicalTrials.gov. RNA-based variant-adapted booster (Pfizer/BioNTech) [Internet]. Bethesda (MD): U.S. National Library of Medicine; 2025. Report No.: NCT07069309. Available from: https://clinicaltrials.gov/study/NCT07069309

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Roshini Dommeti

Published

2025-09-12
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How to Cite

Dommeti, R., S, N. S., M, V. P., & Dommeti, M. S. P. (2025). Brief review on ongoing clinical trials on covid-19 vaccines. Journal of Modern Techniques in Biology and Allied Sciences, 2(3), 10-13. https://doi.org/10.70604/

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Articles

How to Cite

Dommeti, R., S, N. S., M, V. P., & Dommeti, M. S. P. (2025). Brief review on ongoing clinical trials on covid-19 vaccines. Journal of Modern Techniques in Biology and Allied Sciences, 2(3), 10-13. https://doi.org/10.70604/