Preeclampsia in high-risk pregnancy: a case study on diagnosis and management

Authors

  • G Venkata Nagaraju Department of Pharmacy Practice, Hindu College of Pharmacy, Amaravati Road, Guntur, A.P, India
  • Guntur Venkata Srilekha Department of Pharmacy Practice, Hindu College of Pharmacy, Amaravati Road, Guntur, A.P, India

Abstract

Preeclampsia is characterized by the development of hypertension and proteinuria after 20 weeks of pregnancy in women who were previously normotensive. This condition poses risks for significant complications affecting the mother, fetus, and newborn. The aim of this study is to assess the maternal and perinatal outcomes of preeclampsia without severe features in women receiving care at the Government General Hospital in Guntur.

Keywords:

pre ecclampsia, HELLP syndrome

DOI

https://doi.org/10.70604/learnint.v1i1.12

References

1. DC.Duttas textbook of obstetrics

2. oon, L. et al. The International Federation of Gynecology and Obstetrics (FIGO) initiative on pre-eclampsia. Int. J. Gynaecol. Obstet.145, 1 (2019).

3. Magee, L. A. et al. The 2021 International Society for the Study of Hypertension in Pregnancy classification, diagnosis & management recommendations for international practice. Pregnancy Hypertens.27, 148–169 (2022). This paper outlines best-practice guidelines for diagnosis and management of preeclampsia

4. Erez O, Romero R, Jung E, Chaemsaithong P, Bosco M, Suksai M, Gallo DM, Gotsch F. Preeclampsia and eclampsia: the conceptual evolution of a syndrome. Am J Obstet Gynecol. 2022 Feb;226(2S):S786-S803.

5. 5.Macedo TCC, Montagna E, Trevisan CM, Zaia V, de Oliveira R, Barbosa CP, Laganà AS, Bianco B. Prevalence of preeclampsia and eclampsia in adolescent pregnancy: A systematic review and meta-analysis of 291,247 adolescents worldwide since 1969. Eur J Obstet Gynecol Reprod Biol. 2020 May;248:177-186.

6. Battarbee AN, Sinkey RG, Harper LM, Oparil S, Tita ATN. Chronic hypertension in pregnancy. Am J Obstet Gynecol. 2020 Jun;222(6):532-541.

7. Gestational Hypertension and Preeclampsia: ACOG Practice Bulletin, Number 222. Obstet Gynecol. 2020 Jun;135(6):e237-e260.

8. Homer CS, Brown MA, Mangos G, Davis GK. Non-proteinuric pre-eclampsia: a novel risk indicator in women with gestational hypertension. J Hypertens. 2008 Feb;26(2):295-302.

9. Tanner MS, Davey MA, Mol BW, Rolnik DL. The evolution of the diagnostic criteria of preeclampsia-eclampsia. Am J Obstet Gynecol. 2022 Feb;226(2S):S835-S843.

10. Reddy M, Fenn S, Rolnik DL, Mol BW, da Silva Costa F, Wallace EM, Palmer KR. The impact of the definition of preeclampsia on disease diagnosis and outcomes: a retrospective cohort study. Am J Obstet Gynecol. 2021 Feb;224(2):217.e1-217.e11.

11. Phipps EA, Thadhani R, Benzing T, Karumanchi SA. Pre-eclampsia: pathogenesis, novel diagnostics and therapies. Nat Rev Nephrol. 2019 May;15(5):275-289.

12. Jung E, Romero R, Yeo L, Gomez-Lopez N, Chaemsaithong P, Jaovisidha A, Gotsch F, Erez O. The etiology of preeclampsia. Am J Obstet Gynecol. 2022 Feb;226(2S):S844-S866.

13. BERGER M, CAVANAGH D. TOXEMIA OF PREGNANCY. THE HYPERTENSIVE EFFECT OF ACUTE EXPERIMENTAL PLACENTAL ISCHEMIA. Am J Obstet Gynecol. 1963 Oct 01;87:293-305.

14. Labarrere CA, DiCarlo HL, Bammerlin E, Hardin JW, Kim YM, Chaemsaithong P, Haas DM, Kassab GS, Romero R. Failure of physiologic transformation of spiral arteries, endothelial and trophoblast cell activation, and acute atherosis in the basal plate of the placenta. Am J Obstet Gynecol. 2017 Mar;216(3):287.e1-287.e16.

15. Staff AC, Johnsen GM, Dechend R, Redman CWG. Preeclampsia and uteroplacental acute atherosis: immune and inflammatory factors. J Reprod Immunol. 2014 Mar;101-102:120-126.

16. Poon, L. et al. The International Federation of Gynecology and Obstetrics (FIGO) initiative on pre-eclampsia. Int. J. Gynaecol. Obstet. 145, 1 (2019).

17. Magee, L. A. et al. The 2021 International Society for the Study of Hypertension in Pregnancy classification, diagnosis & management recommendations for international practice. Pregnancy Hypertens. 27, 148–169 (2022). This paper outlines best-practice guidelines for diagnosis and management of pre-eclampsia.

18. Pittara, T., Vyrides, A., Lamnisos, D. & Giannakou, K. Pre-eclampsia and long-term health outcomes for mother and infant: an umbrella review. BJOG

19. O’Gorman, N. et al. Multicenter screening for pre-eclampsia by maternal factors and biomarkers at 11-13 weeks’ gestation. Ultrasound Obstet. Gynecol. 49, 756 (2017).

20. Amaral, L. M., Cunningham, M. W. Jr, Cornelius, D. C. & LaMarca, B. Preeclampsia: long-term consequences for vascular health. Vasc. Health Risk Manag. 11, 403–415 (2015).

Published

2025-02-21
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How to Cite

Gorre, V. N., & Guntur, V. S. (2025). Preeclampsia in high-risk pregnancy: a case study on diagnosis and management. Learnovate-International, 1(1), 1-4. https://doi.org/10.70604/learnint.v1i1.12

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How to Cite

Gorre, V. N., & Guntur, V. S. (2025). Preeclampsia in high-risk pregnancy: a case study on diagnosis and management. Learnovate-International, 1(1), 1-4. https://doi.org/10.70604/learnint.v1i1.12