A study to assess the efficacy of various treatment approaches used in gastritis

Abstract

Gastritis, an inflammation of the gastric mucosa, arises from diverse etiologies including infections, autoimmune disorders, and chemical irritants, and if left untreated, may progress to ulcers, gastric carcinoma, or lymphomas. This study aimed to evaluate the effectiveness of various treatment strategies for gastritis, encompassing pharmacological therapies, dietary interventions, and lifestyle modifications. Conducted as a six-month observational cohort study at SVS Medical College and Hospital, Mahbubnagar, it included 100 adult patients aged 18–65 years with confirmed gastritis diagnoses. Treatment regimens consisted of proton pump inhibitors (PPIs), H2-receptor antagonists, antacids, antibiotics for Helicobacter pylori, and tailored dietary guidance. Clinical evaluations and patient-reported outcomes were recorded, with data analyzed using SPSS v23 and GraphPad Prism v9, considering p < 0.05 as statistically significant. The majority of participants were aged 55–65, with a slight male predominance (52%) and urban residency (65%). A strong correlation was found between the consumption of spicy and fatty foods and the severity of symptoms (p < 0.05). PPIs were the most commonly prescribed agents (60%), while dietary changes were recommended for half of the cohort. Notably, 61% of patients achieved moderate gastrointestinal quality of life scores (GIQLI 70–89), and high rates of treatment adherence (85%) and satisfaction (92%) were observed. The findings affirm that a comprehensive, patient-centered approach integrating medication, nutritional counseling, and education enhances symptom control, promotes healing, and improves quality of life. These outcomes support the adoption of integrated treatment models and highlight the potential for future research into personalized care and digital health interventions in gastritis management.